I wish I could pick up a PRS - even a bottom of the line one - for 300 bucks, and not have to worry about destroying it and never being able to buy another!
I just went and bought an Epiphone SG for my wife last night (just something to kick around at band practice) - 60 bucks.
Guitar collecting is probably pretty darned fun. Unfortunately, with lefties it's either an exercise in futility or a very expensive hobby. There aren't many mid-range guitars out there, and almost none that people are selling, even in this economy.