Mahavishnu? Innovative AND influential, maybe? There are people who play guitars by dropping pebbles on them, the whole "prepared" guitar New Yawk art scene and all. Elliot Sharp, Glen Branca, yaak. Not so influential... I can't do fives, but I will say there was a long stretch where everything on country radio owed a huge debt to the Allman Brothers, twin leads, slide mania; at the same time (85-98?) everything "new" on rock radio owed far more to Zeppelin than to Hendrix, to my ear. No Zepp, no metal, no shred, no Aerosmith hence no Guns 'n' Roses....
I'm currently obsessed with OHM, and Oz Noy, in this day and age I'm really happy to find bands and guitarists who play really new, fresh things and go out of their way to avoid cliches. You need both your innovators and your consolidators to keep moving, but while I love Petrucci's "Suspended Animation" and Kiko Loriero's "No Gravity" it's almost like listening to "The Encyclopedia of Rock Guitar." I've GOT to put John McLaughlin at the top of any "fives": no Mahavishnu - no fusion, no Shakti - no World Music. He pretty much introduced the notion of classical-level chops into electric guitar playing - studpuppies like Zappa, Beck and Santana were terrified of Mahavishnu at full bore. Funny that I hate fusak and "world" music and love McLaughlin's work, but that's almost the definition of innovation, right?