If you think about it, and experiment a bit with thumb positioning, you may find as I have, that hand size and neck thickness aren't really that interrelated. Finger length and neck width, yes... but put all your fingertips and thumb together and point it at your eye, then look at what happens to your available finger spacing when you start to pull your thumb away - Voila! It might even seem as though people with small hands should use thicker necks....
I could simply never get on with "Wizard" necks until a bandmate told me the secret there, which is to keep your thumb right in the middle of the neck and point your thumb straight backwards toward the tuners. Viola! I cringe a bit when I read sumgai posting that their Squier Boofdelootie has the "perfect neck for them" and they're on a search for a "luthier" to duplicate it - and the only guitar they've ever tried to get on with for more that three minutes was the mighty Boof... one should ideally play as many different necks as possible and make a manly attempt to get the most out of each one, before even thinking about the "perfect" neck.
All else being equal (it never is) I have found that the more meat in a neck, the better the guitar sounds. Makes more diff than body woods, for sure. I find the 1" boatneck style, even down to a .960" one I got at USAG (AKA "super-soft vee"), is a little more comfortable for long periods that the 1" "C" or Fatback. I'm pretty sure that the extra few percent of wood in the boat does probably sound that much better... Cello!
It's always impressive to watch the long twirtchy spiderfinger guys like Steve Vai and Paul Gilbert zipping around and about the neck, but if adequacy issues plague you just look up some videos of Shawn Lane and Danny Gatton.
http://www.youtube.com/watch?v=RyjtW-rvWoQ&feature=list_related&playnext=1&list=AVGxdCwVVULXfeDopD5OsZ96xsA5wWbLjN
http://www.youtube.com/watch?v=iw1sojT-V1c&feature=related
They both have the left hand that's like a Warner Brothers cartoon hand, a big blob with some wiggly little nubs attached.... so when you've learned that Shawn Lane solo, lets us know which neck worked out best! Ahem. :hello2: