There is so much more than "type" of tube, but also the manufacturer, when it was manufactured, even which plant it was made in, the circuit its used in.... including, but not limited to... the transformers (the BIGGIE OF BIGGIES), coupling capacitors, actual vs drawn circuit values, wall voltage (and thus B+), type, size and condition of power filtration, rectifier type... tube, solid state, what kind of tube etc etc, speaker, including size, type, cone material and age, voice coil and former, type of spider and ribs, and surround and ribs, if the cone is straight, belled, parabolic, radiused, ribbed, textured, how thick it is,
There is just so much to the whole story besides type type.
When you say, I'm going to use a KT66, its like saying, I'm using a tele flat bridge. After that, all bets are off, and everything else matters a lot.
carry on.....