I agonized a bit about stainless steel frets the first time I tried them, but there's nothing to worry about and good reasons to be excited about it. They feel/play substantially better, last dramatically longer, and don't affect the sound of the instrument. Once you have a neck fretted that way, you'll wonder why everybody doesn't use them.
The reason for that is manufacturers/techs have issues with them in that they're harder to work with than the traditional nickel/silver fretwire. It's a pretty hard alloy so they'll prematurely wear traditional fretworking tools, in some cases rendering them nearly useless before you can even finish the first neck. Most techs will charge an extra $150 or so on a re-fret if you want stainless or gold(EVO) wire because they're charging for the tools they're going to have to replace, as well as the extra time involved.
That wire also doesn't "give" or bend easily, so fretting gets a little more tedious on compound radius necks as each fret has to be radiused for its position on the neck. Otherwise, you get a lotta springback that can only be fixed by removing, re-radiusing then reinstalling the offending fret. No fun. Oddly enough, this is a bigger issue for manufacturers than it is for techs, as they use automated fretting tools that depend on the fretwire being soft enough to be somewhat conformal to the neck radius. Those auto-feed/cut tools make initial installation a 3 minute job for the whole neck. But, if every fret is unique, those tools are useless and fretting becomes a manual (read: expensive) operation.
Then, leveling, crowning, dressing and polishing takes a little longer. Where a lick and a promise works on nickel/silver wire, stainless wants some elbow grease.
All of those things mean a higher cost of entry. But, that's just on the initial installation/setup, and how much higher depends on whether the folks who do that work have made the investment in the tools/procedures to overcome those hardships. Tools exist that will deal with stainless wire without destroying themselves in the process. Custom radiusing for compound radius necks can be dealt with by pre-radiusing/cutting in bulk. It's not that tough, and I think we'll see stainless fretted necks in increasing numbers as time goes on. They're just too nice.