I have a nice, light chambered ash body with a maple top and it's well within the usual weight range of solid bodies. If you lose as much as a quarter of the weight of the solid body by chambering, you're doing pretty good, and you'll probably lose less. So unless you get a really unusually light body (like, sub-three-pounds) and an unusually heavy neck (solid ebony, perhaps), with very heavy tuners, the strap button point on a Strat body will keep things balanced just fine - especially once you add the trem and pickups. If you were going after a telecaster, maybe, but even so, pretty unlikely.